Flash generation of α-(trifluoromethyl)vinyllithium and application to continuous flow three-component synthesis of α-trifluoromethylamides.
نویسندگان
چکیده
α-(Trifluoromethyl)vinyllithium was generated and used for the reaction with electrophiles at -78 °C in a flow microreactor although the batch reaction should be carried out at ca. -100 °C, and the method was applied to continuous flow three-component synthesis of α-trifluoromethylamides.
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عنوان ژورنال:
- Chemical communications
دوره 50 95 شماره
صفحات -
تاریخ انتشار 2014